My Screen does not respond to touch, is jumping about, or has un-commanded response particularly when it rains or it is extremely dusty?

This is not uncommon and is due to the screen being activated by water or dust. Using the Buttons App (a system app available on all our devices), configure a hardware button to enable/disable screen touch. When riding in the rain or on very dusty places lock the screen touch!

I will not have a SIM Card in the device will DMD2 work, including turn by turn navigation?

In short yes. Internet connectivity is only needed to conduct online search for addresses, etc, download maps and GPX data and conduct updates. Otherwise it can remain offline and fully functional.